In From Bud to Brain, I traced how marijuana research gradually morphed from focusing on the cannabis plant (botany) to exploring the brain’s natural endocannabinoid system (neuroscience) and, ...

A study published in Cell Reports found that the brain’s amygdala releases endogenous cannabinoid molecules when a person experiences stress. These molecules mitigate the incoming stress alarm from ...

Alcohol binge increases intestinal permeability by activating intestinal epithelial CB1R-ERK1/2 signalling with subsequently reduced differentiation and downregulation of tight junctions (left).

Over the past two decades, a great deal of attention has been given to marijuana – also known as pot or weed. As of early 2023, marijuana has been legalized for recreational use in 21 states and ...

A new systematic review published in Brain, Behavior, and Immunity suggests that using cannabinoids does not have a single, straightforward effect on the human immune system. Instead, regular use ...

Cannabis can soothe the intestines and bladder, but too much can cause trouble. Cannabis has been used for millennia to treat cramps and diarrhea. The basic mechanism for this effect is the presence ...

Over several decades, researchers have identified more than 140 active compounds, called cannabinoids, in the cannabis plant. Lauren DeCicca / Getty Images The 1960s was a big decade for cannabis: ...